How Long does it take Diflucan to Work?

Diflucan is a brand name for a medication whose medical name is fluconazole. This medication is used in treating numerous fungal infections. It is used commonly in the treatment of female vaginal yeast infections, known as Candida vulvovaginitis.

Vaginal yeast infections begin when fungal microorganisms in the family Candida have been overgrowing. This leads to a burning sensation, irritation and itching in your vaginal area.

Diflucan fights this virus by damaging the cellular structure of Candidas and by inhibiting its reproduction ability. Depending on how severe your infection is, Diflucan may be prescribed in a single dose, or as a short series of anti-viral doses taken three days apart. Long-term treatment may be taken for 10 days to two weeks.

Symptoms of Vaginal Yeast Infections

Yeast infections cause soreness or itching in your vaginal area. There may be pain during intercourse and urination. Some women develop a white, clumpy, thick discharge that is odorless and resembles cottage cheese.

The symptoms above will more likely occur in the week preceding your normal menstrual period.

How Long Does it take Diflucan to Work?

For uncomplicated, mild infections, this medication is prescribed as one dose of 150 mg. Improvement is generally noted in one to three days. If one dose does not fully relieve your symptoms, or if you have a more severe infection, Diflucan may be prescribed in three doses.

With these regimens, the symptoms are expected to improve within a week to two weeks. If your symptoms continue even after proper treatment, your physician may prescribe Diflucan for everyday use for 10 days to two weeks. It can even be continued once each week for a six-month period, if needed.

Other Methods of Infection Control



Bacteria and Candida yeast are found in any normal vaginal environment. The problems occur when the balance of good to bad bacteria is disrupted. This Candida overgrowth may be brought on by oral contraceptives, antibiotics, HIV, diabetes or pregnancy. Habits that will trap moisture and heat in your vaginal area may also start overgrowth.

Diflucan is normally an effective, speedy way to control vaginal Candida overgrowth. Several personal habits that are helpful in the prevention of overgrowth include:

  • Wearing undergarments made of cotton, rather than synthetic materials
  • Avoiding clothing that fits tightly
  • Avoiding using harsh antibacterial cleansers and soaps
  • Avoiding the wearing of gym clothes or bathing suits for any longer than you have to

Most women experience a yeast infection at least once. If your symptoms persist even after proper treatment, your physician will want to evaluate your case for other risk factors or potential causes.


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