skeleton-778069_1920Polyarthralgia is a condition involving multiple joints pain which is more common in elderly. It is mostly related to rheumatoid arthritis, but it is not a disease by itself. It can be a symptom of many diseases, that’s why it is important to convey thorough investigation about the root problem. The pain in the joints can start from mild to a much vigorous one. It is usually described as a sharp, dull, stabbing pain in the joints leading to disability in the future. It progresses over time, starting from the age of 30 to 50 years old people. The doctor should conduct an anamnesis in depth and physical examination in order to find the cause and begin with the treatment. This way, we can prevent any adverse effects.

Signs For Differential Diagnosis

Rheumatoid Arthritis

It usually begins at the age of 40 or even later. It is a chronical inflammatory disease which affects the lining of the joints which result in swelling and morning stiffness that lasts for hours. It can be accompanied by fever and weakness, as well as rheumatoid nodules under the skin. It is more common in women and starts with smaller joints first, then spreading to knees, hips and shoulders. It progresses over time, and after a while, it can have radiological evidence of bone erosion. It causes symmetrical changes in the joints, usually starting with metacarpophalangeal joints, proximal interphalangeal joints and wrist joints.

Seronegative Arthritis

Without the presence of the rheumatoid factor in the blood (RF), a disease of an arthritis is called seronegative. It is similar to rheumatoid arthritis, except it usually comes asymmetrical and affects different joints. It has the same symptoms that include morning stiffness, swelling, but the joints that are being damaged are hip joint, knee, lower back, elbow, etc. It can be associated with some diseases like psoriasis, spondyloarthritis, enteropathic arthritis and reactive arthritis.


Arthralgia simply means pain in the joint area. It can affect one or more joints, including small ones or bigger ones. There are many underlying causes and they have to be examined and diagnosed. The main thing about arthralgia is that there is no inflammatory reaction, that’s why this is not called “arthritis”. It can be due to an injury, infection, degenerative disease and immune disorders, so right diagnose is important.


This is the type of arthritis that it’s called “wear-and-tear” disease. The name itself tells us a bit about the main cause of this condition, which is a tear of the cushion of the cartilage. It also comes with pain, stiffness and joint swelling. There is no proper cure for it and it is a degenerative disease which worsens over time. Characteristic pain in the morning doesn’t last for long like in RA and goes away after a few minutes. It doesn’t have a proper cause, but there are some factors that can affect the disease appearing like genes, excess weight, overuse of joints.


Fibromyalgia affects muscle and soft tissue, leading to chronical muscle pain accompanied by tendons tightness and fatigue. A person can also sense numbness in certain parts like jaw, legs, arms, feet. There is an event of cognitive dysfunction such as forgetting, the difficulty of concentrating. This is called “fibro fog”. It is more common in women than in men.

Proper Diagnosis Of Polyarthralgia

There are many symptoms and factors that need to be stated. A lot of diseases don’t have to appear in a characteristic way nor all of the symptoms need to be expressed in order to establish a connection to a certain disease. Some of the conditions require treatments such as lifestyle change and small things that you can start doing right away.

  1. As for simple arthralgia, if you are not sensing some inflammatory symptoms and it doesn’t last a long time, you can try with analgesics and nonsteroidal anti-inflammatory drugs like ibuprofen. This should help you relieve the pain. If you experience other changes than in your joints, you should consider going to the doctor, given that something different might be happening.
  2. As to osteoarthritis, you should know that you can influence on the course of the disease by changing your lifestyle, meal plan, activity. You should start with optimal activity in your daily routine and also possible physical therapy as it can help you with stiffness and pain. You should stick with a good meal plan and strive for optimal weight since the further pressure can damage your joints more. You can also include some nonsteroidal anti-inflammatory drugs for pain reduction.
  3. Rheumatoid arthritis has no cure, but it can slow down with a vitamin D therapy. People use drugs such as nonsteroidal anti-inflammatory drugs (ibuprofen, naproxen). Steroids can help with inflammation of the joints, such as prednisone, reducing the swell Disease-modifying antirheumatic drugs (DMARDs) are used as a therapy to slow down the progression of the disease and help with the symptoms. Some common DMARDs are sulfasalazine, methotrexate, leflunomide. The doctors can also opt for surgery if the drugs fail to slow down joint damage. It can lead to deformities correction and pain reduction. It can be joint fusion, tendon repair or total joint replacement.